Letybo: A New Generation of Wrinkle-Relaxing Treatment
Say hello to smoother, refreshed skin with Letybo—the newest FDA-approved botulinum toxin type A injectable designed to reduce the appearance of fine lines and wrinkles. Discover everything you need to know about this exciting new option.
FREQUENTLY ASKED QUESTIONS
Letybo is an injectable botulinum toxin type A, used to temporarily smooth moderate to severe facial wrinkles—especially glabellar lines (frown lines between the eyebrows). Like Botox and Dysport, it works by relaxing the facial muscles that create dynamic wrinkles over time.
Letybo stands out for its:
Manufactured by Hugel, a South Korean aesthetics leader, Letybo has been trusted for years in Asia and Europe and received FDA approval in 2023 for use in the U.S.
- Highly purified formula
- Smooth injection experience
- Natural-looking results
- Global reputation (over 10 million vials sold worldwide)
Manufactured by Hugel, a South Korean aesthetics leader, Letybo has been trusted for years in Asia and Europe and received FDA approval in 2023 for use in the U.S.
Letybo is FDA-approved for:
It is also commonly used off-label by licensed providers for:
- Glabellar lines (frown lines between the brows)
It is also commonly used off-label by licensed providers for:
- Forehead lines
- Crow’s feet (lines around the outer corners of the eyes)
Onset: 3 to 5 days
- Full results: 10 to 14 days
- Duration: Typically lasts 3 to 4 months, depending on metabolism and area treated.
Most patients say it feels like a tiny pinch. The treatment is quick, typically done in under 15 minutes, with no downtime. A numbing cream can be applied if desired.
Common, mild side effects include:
These usually resolve within a few hours to a few days.
- Redness or swelling at the injection site
- Temporary bruising
- Mild headache
- Slight tenderness
These usually resolve within a few hours to a few days.
Yes. While rare, serious side effects can occur and may include:
In very rare cases, the botulinum toxin can spread beyond the injection site and cause botulism-like symptoms, which may include muscle weakness, breathing issues, or loss of bladder control. This is extremely rare but must be taken seriously.
Seek medical attention immediately if you experience symptoms like difficulty breathing, speaking, or swallowing.
- Drooping eyelid (ptosis) or eyebrow
- Asymmetry or uneven smile
- Double vision or blurred vision
- Difficulty swallowing or speaking
- Allergic reactions (rash, itching, shortness of breath)
In very rare cases, the botulinum toxin can spread beyond the injection site and cause botulism-like symptoms, which may include muscle weakness, breathing issues, or loss of bladder control. This is extremely rare but must be taken seriously.
Seek medical attention immediately if you experience symptoms like difficulty breathing, speaking, or swallowing.
Letybo may not be suitable for:
Always share your full medical history during your consultation.
- People who are pregnant or breastfeeding
- Those with neuromuscular disorders (e.g., ALS, myasthenia gravis)
- Individuals who have had allergic reactions to botulinum toxin
- Anyone with active skin infections at the injection site
Always share your full medical history during your consultation.
Dosage varies, but here are general estimates:
Your provider will tailor the treatment to your facial anatomy and goals.
- Glabellar lines: 20–25 units
- Forehead lines: 10–20 units
- Crow’s feet: 12–24 units (6–12 per side)
Your provider will tailor the treatment to your facial anatomy and goals.
Yes! Letybo can be part of a full-face rejuvenation plan and pairs well with:
- Dermal fillers
- Microneedling
- Chemical peels
- Laser treatments
Before Treatment:
After Treatment:
- Avoid alcohol, ibuprofen, or blood thinners for 24–48 hours
- Come with clean skin (no makeup) if possible
After Treatment:
- Do not lie down for 4–6 hours
- Avoid rubbing or touching treated areas
- No intense exercise or facials for 24 hours
- Mild swelling or bruising is normal—use a cold pack if needed
The effects of all botulinum toxin products, including Letybo, may spread from the area of injection to produce symptoms consistent with botulinum toxin effects. These symptoms have been reported hours to weeks after injection. Swallowing and breathing difficulties can be life threatening and there have been reports of death. Letybo is not approved for the treatment of spasticity or any conditions other than glabellar lines.